ARC is the only national charity helping parents and healthcare professionals through antenatal screening and its consequences. ARC offers non-directive individualised information and support to parents who are making decisions around antenatal testing. ARC gives long term support to parents whatever decision is made about the future of their pregnancy through a national helpline, coordinated network of volunteer parent contacts, password-protected internet support forums, face-to-face meetings, regular newsletters and a range of publications for parents and their families.

Every day, we match incredible individuals willing to donate their blood stem cells or bone marrow to people with blood cancer and blood disorders who desperately need lifesaving transplants. It all began in 1974. With her three-year-old son Anthony in urgent need of a bone marrow transplant, Shirley Nolan set up the world’s first register to match donors with people in desperate need. Now, we help four people each day find that lifesaving match.

Anti-Slavery International, founded in 1839, is committed to eliminating all forms of slavery by campaigning for its eradication, supporting local organisations’ initiatives to release people, and pressing for implementation of laws against this abuse. For further information see www.antislavery.org

Ape Action Africa work on the front line of conservation - saving endangered primates from the illegal bushmeat and pet trades. At our Mefou sanctuary we provide rehabilitation and long-term care in a protected environment for orphaned monkeys and apes. We work closely with the Cameroonian people through social support & education programs so that we can be provide long term protection for Cameroon's primates, and keep apes and monkeys in the wild where they belong.

Committed to finding better and kinder treatments for children with cancer

Action on Poverty are a small international charity with a big impact on tackling poverty. We work with local expert partners in Uganda, Sierra Leone, Tanzania and Kenya to provide people living in the harshest poverty with the opportunities they need to earn a living and transform their lives, and we can only do this with the help of supporters like you. Your fundraising efforts will help us work with people who struggle to overcome poverty the most: women, people with disabilities, young people and refugees. You’ll make it possible for us to stop dangerous child labour and return children to school; to train women in business skills and learn a trade, earning an independent income for the first time; to share climate-resilient agricultural skills with refugees, so they can grow vegetables to eat and sell despite climate shocks; and to provide everyone with the opportunity to break the cycle of poverty, for good.

Raising money for breast cancer research projects and donations to services caring and supporting those affected by breast cancer through the sale of art and sculpture

The Arthur Rank Centre, supports rural churches and their wider rural communities. Working together, we confront disadvantage and take social action, tackling hidden poverty, isolation and loneliness, lack of affordable housing, poor transport links and other challenges of living in the countryside.

Arthur Rank Hospice Charity supports people in Cambridgeshire living with an advanced serious illness or other life-limiting condition and those who need end-of-life care. Our ‘Outstanding’ services are provided free of charge to patients and their families. Our aim is to provide the highest quality care, helping them to make every moment count. We care for more than 4,100 patients each year at our Hospice in Cambridge, the Alan Hudson Day Treatment Centre in Wisbech and in patients’ own homes via the Arthur Rank Community Team. This care supports people to improve their quality of life and fulfil their end of life choices. Alongside the care provided by our Inpatient Unit, Living Well services and Hospice at Home teams, patients can access: patient and family support; lymphoedema care; complementary therapy; medical and pain outpatient clinics; and advice from the clinical nurse specialists within the Specialist Palliative Care Home Team. Our programmes are practical, holistic and tailored to the individual patient, family member or carer and may also include rehabilitative support, physiotherapy, occupational therapy and psychological support. It will cost £11.51 million in 2022/2023 to run our services, which are provided free of charge to patients and their loved ones. We have currently secured £7.07 million from the NHS, meaning that £4.44 million needs to be raised through donations, fundraising activities and trading. We are extremely grateful to our local community for the continual dedication, commitment and generosity they show in supporting us to meet this target. For further information, please visit arhc.org.uk

A4D develops innovative, person-centred arts programmes to re-energise and inspire people in the early stages of dementia and carers, to help them live better for longer at home. Our website uniquely signposts arts events nationwide for people living with dementia; and we provide early stage dementia awareness training at London arts venues for arts facilitators from all over the country. The 500-plus workshop leaders we have trained to date are delivering arts opportunities to well over 10,000 people living with dementia each year. A4D focuses on what people can achieve - often very much more than they imagine.

Transport Charity helping older and vulnerable adults to access their medical appointments, social events and shopping. Providing volunteer drivers to transport them safely and to offer support as needed.

Ashinaga provides financial support and emotional care to orphaned children worldwide. Every year, more than 8,000 orphaned students receive Ashinaga Scholarships. Over the past 55 years, Ashinaga has helped around 110,000 students gain access to education.

The Association of Carers support unpaid carers in East Sussex. We offer free, volunteer-led services that encourage independence and help reduce social isolation. A Carer is someone of any age who provides unpaid support to family or friends, who could not manage without this help. There are 6 million people in the UK who are family carers (1 in 8 adults). Carers save the economy £119 billion per year.

One in five of us has a lung condition. Millions more are at risk. We’re the only UK charity looking after the nation’s lungs. We offer hope, help and a voice. Our research finds new ways to prevent, treat and cure lung disease. Our support gives people who struggle to breathe the skills, knowledge and confidence to take control of their lives. Together, we’re campaigning for clean air and better lung health. Your support will take us one step closer to a world without lung disease.

Ataxia is a type of neurological condition that affects balance, speech, and co-ordination. Ataxia is progressive, meaning it gets worse with time, until people become entirely dependent on others for all their needs. Over 10,000 people in the UK have ataxia and there is currently no cure. Ataxia UK is the national charity for people affected by ataxia and we provide unique services and support, including a dedicated helpline, Branches and Support Groups, together with closed social media groups, events and conferences where people can meet and share information, a quarterly magazine and monthly e-newsletter, a website with lots of information and a discussion forum, publications, films, and reports. As well as our specialist services, we have spent over £5 million on research since 2000 into possible treatments and cures for ataxia. Our vision is a world without ataxia and, with the help of our brilliant supporters, we are working towards this every day.

Atlantic Pacific International Rescue is an NGO dedicated to combating global drowning through the construction and deployment of lifeboats and training individuals in lifesaving techniques.

We provide a listening and spoken language programme, called Auditory Verbal therapy, so that parents and carers can maximise their deaf child’s listening, talking and social skills. We work with families across the UK and train health and education professionals in Auditory Verbal practice around the world through our internationally accredited training programmes. We want all deaf babies and children to have the same opportunities in life as their hearing peers. Our aim is that all families who want their child to learn to listen and talk are able to access an Auditory Verbal therapy programme through publicly funded services over the next 10 years. AVUK’s outcomes are life changing. 80% of all children who spend at least two years on our pre-school programme achieve age-appropriate language. Children are equipped with listening and talking skills, as well as the social skills and confidence to succeed.

Autism Anglia is an independent charity which provides education, care and support to people with autism and autistic spectrum conditions. Our services enable children, young people and adults with autism from across the region to live as independently as possible and experience choice and inclusion in society.

We provide services for autistic children, young people and adults, and their families across the county of Bedfordshire.

Autism East Midlands has, for over 50 years, strived to create a world which recognises, understands and values autistic people, and where they and their families (and supporting professionals) receive the support they need - enabling autistic people to live their lives with dignity, choice and independence.

Our mission is to enable people with autism in Hampshire to develop and achieve their full potential by providing and developing person centered services, expert advice, education and support, promoting the awareness and understanding of autism and signposting interested parties to information and services that may be of help.

Autism Jersey, supporting people with autism, their families and carers to lead a full and inclusive life.

Autism NI (PAPA) is Northern Ireland’s main Autism charity.  We support a network of 17 branches and support groups across Northern Ireland and provide free advice and information, a helpline and support for parents and carers, an Autism library and a wide range of training courses.

Raising the awareness of autism through sailing and assist autistic people to access sailing through our charity.

We help families throughout and following their children's autism diagnosis. Offering advice, training and support.

Autistica is the UK’s national autism research charity. We focus on giving autistic people the opportunity to live long, happy, healthy lives. We do this by funding research, shaping policy and working with autistic people to understand their needs. With your help we can make more of a difference. We know that every autistic person is different. And we know that autism comes with both strengths and challenges. But there’s lots we don’t know. Research is the best way to improve understanding, find new ways to support people and families, and change lives for the better. We are making more of a difference by: Funding, shaping and growing research across the UK, developing new therapies, campaigning for better services and shaping national policy, and sharing evidence-based tools, resources and information.

Awyr Las is the NHS Charity in North Wales. Through Awyr Las you can help to provide new equipment, better facilities and spaces, training, research, special projects and patient comforts which make a real difference to patients and their families in North Wales.

The B&Q Foundation believes everyone needs a place to feel at home