The One YMCA covers all Buckinghamshire, Hertfordshire and Bedfordshire areas, providing services and a range of programmes to support your local community. We have 5 areas support: Family & Youth Work, Health & Wellbeing, Housing, Training & Education and Support & Advice. We deliver a range of programmes and services that tackle the issues facing local people and ensure that there are opportunities for young people throughout our work, from apprentices to work experience and childcare to youthwork. The One YMCA inspire to create supportive and energising communities that are open to all, where young people can truly belong, contribute and thrive.

One25 reaches out to women trapped in, or vulnerable to, street sex work, supporting them to break free and build new lives away from violence, poverty and addiction. We are a Bristol-based charity, founded in 1995 as the only organisation specifically supporting street sex-working women. Our vision is a community where all women are valued and able to live fulfilled lives without the risk of being trapped in sex work.

OnSide's mission is to build, deliver and sustain a network of 21st century youth centres across England which will give young people top quality, safe and affordable places to go in their free time.

We believe that every child has the right to shelter, food & love. Today, 1,890 babies will be born in Malawi. 320 will become orphans. 87 will die before their first birthday from malnutrition or illness. We’re the only organisation in southern Malawi able to feed, house and care for these babies and support their return to their communities.

For the public benefit, to relieve the needs of the families of those serving and former members of the Armed Forces who are diagnosed with or who are experiencing symptoms of post-traumatic stress disorder (PTSD) by working with Armed Forces agencies, health services and mental health expertise and: raising public awareness of PTSD; providing support groups and related services to enable those families to best support their loved ones; providing grant funding for family oriented short breaks and activities.

There are over 39 million blind people in the world. 80% of these cases are avoidable and 90% live in developing countries. Orbis is a global charity, dedicated to preserving and restoring the sight of the poorest people in the poorest communities across the world.  

Over 58,000 people will be diagnosed with prostate, testicular or penile cancer every year in the UK. Orchid exists to save lives from testicular, prostate and penile cancers through a range of support services, pioneering research and promoting awareness.

We provide personalised services supporting people with learning and physical disabilities and their families and carers. Our services include a wide range of activities both at our large and pleasant centre at Wright Road and in the community. We also run social enterprises that include the manufacture of our Genesis Garden Furniture and the Green Bike Project.

Our mission is to create a world which enables underprivileged girls and boys living in Indian slums to become role models within their communities. The OSCAR Foundation uses the power of football to teach the importance of education and all OSCAR children must attend school. Education transforms disadvantaged communities and provides young people the tools they need to fight poverty for the next generation. OSCAR International works closely with The OSCAR Foundation in Mumbai, raising awareness, funds and creating opportunities for children living challenging lives. OSCAR has one simple rule. No school, no football.

OURMALA provides specialist trauma yoga to people under international protection in the UK including refugees, asylum seekers, survivors of trafficking and modern day slavery.

Ovacome is a UK- wide support network providing information and support for everyone affected by ovarian cancer. Ovarian cancer is the fourth most common cancer among women in the UK, with around 6, 800 new cases each year.

Action. One third of our name and 100% of what we’re about. And while we’re talking numbers, here’s another: one woman dies in the UK from ovarian cancer every two hours. Although five-year survival rates for ovarian cancer are improving, other cancers, such as breast cancer, had better survival rates two generations ago than ovarian cancer does today. We’re here to change all that. And we’re following two routes to achieve that change: awareness raising and scientific research. Over the last fifteen years, our efforts to fund and facilitate the very best ovarian cancer research have achieved dramatic results. But, of course, there’s more work to be done. Thanks to the continuing generosity of our supporters, we’re now committed to funding the next generation of research and to accelerating progress in three main areas: preventing the disease, diagnosing it early, and developing effective, personalised treatments. We believe this approach will help more women survive ovarian cancer than ever before. Take action with us now and transform the lives and prospects of women today and for generations to come.

Our charity supports wards and services across Northern Devon and areas of North Cornwall to provide care and equipment that is over and above that provided by the NHS. We have launched the Cancer and Wellbeing Centre Appeal to raise funds to build a state of the art information and support centre for local people affected by cancer. One in two people will get cancer at some stage in their life. In Northern Devon we have 9000 cancer referrals each year, and unfortunately, in our area 1700 patients annually are diagnosed with cancer. The good news is that people are now living longer with cancer and we want to help them and their family/carers. Once built, this incredible centre, with overnight accommodation, will be the first dedicated centre of its kind locally. This will be a significant step forward to meeting the rising demand for cancer services locally, and provide support from diagnosis to after care. Cancer can affect every part of your life and people need financial, emotional and practical support, as well as medical treatment. Whether they're the patient, are caring for someone or are simply worried about cancer, the centre will provide a place to come to find a wide range of services. For instance, we hope to provide complementary therapies, Reiki and reflexology, counselling, support groups and nutritional advice, all under one roof, and in a relaxing non-clinical environment. And, when it’s needed most, new overnight accommodation will be accessible to patients, their family and loved ones. To date with public support we have raised £800k but there is still a long way to go towards raising the £1.5 million needed to make this a reality. The new centre, at North Devon District Hospital, will mean that no one going through cancer treatment in Northern Devon will have to do it alone. It’s only with public support that we can make this happen.

Overcoming MS is the world's leading multiple sclerosis healthy lifestyle charity. We help inform, support and empower everyone affected by MS.

Overgate Hospice opened in 1981 and has now been running for 30 years.  During all of that time we have relied and still rely on the local people of Calderdale to raise the funds needed to keep the Hospice open.  Our running costs have now reached £2.8 million, of which only approximately 28% is given to us by the NHS.  This means that we need to raise £2.2 million a year to keep our doors open to the Calderdale area; a massive £6,100 is needed every day.  Because you care, we can. Just £5 could pay for an in-patient's daily meals, or £8 could pay for a patient's clinical supplies for a day, or a wonderful £50 could contribute towards a patients care costs. At Overgate we have a 12 bed inpatient unit, providing both end of life and respite care.  There are doctors and nurses providing 24 hour care to the patient whilst supporting families. All the doctors and nurses at the hospice have been specially trained for palliative care.  We provide care for people with life limiting illnesses such as multiple sclerosis, motor-neurone disease or cancer. 

Human first, amazing second Oxfam is a vibrant global movement of dedicated people fighting poverty. Together. Doing amazing work. Together. People power drives everything we do. From saving lives and developing projects that put poor people in charge of their lives and livelihoods, to campaigning for change that lasts. That’s Oxfam in action.

Oxford Hospitals Charity helps transform our local hospitals - the Oxford Children's Hospital, John Radcliffe, Horton General, Churchill and NOC - funding the latest medical equipment, research and facilities.Thank you so much for your amazing support. Find out more at www.hospitalcharity.co.uk

Oxfordshire Association for the Blind provides support to anyone in the county affected by sight loss. The charity began in 1877 and now supports around 3,000 people annually, with the help of over 100 volunteers. Our services include: the provision of information, advice and equipment; social and emotional support (such as social/sporting groups, home visiting, support for families/carers, and counselling); technology training; a programme for children, young people and families; and awareness training. We also run an Advisory Desk at the Oxford Eye Hospital, offering support at the time of diagnosis. We run Oxfordshire’s only visual impairment resource centre and are the only organisation of our type in the county. Our work is strongly supported by the Eye Hospital, statutory services, and many other organisations. Our vision is a society in which visually impaired people are accepted, included and able to contribute in a meaningful way. We are fully inclusive – our services are free of charge and available to everyone who needs them.

Oxfordshire Mind helps over 30,000 people with mental health challenges every year. They promote good mental health through the provision of high quality services and campaigning for positive change. Their services include housing, talking therapies, benefits advice, a confidential and free information line, courses (such as ‘practical ways to wellbeing’), physical activity programmes, volunteering opportunities, and they facilitate over 60 peer-support groups each week.

Pace is a specialist charity that is committed to ensuring that children with neurodisabilities have the opportunity to reach their fullest potential in life and can take their place in the world.

Paces is a specialist centre, school and charity all rolled into one! We support children and adults living with neurological conditions such as Cerebral Palsy, Stroke, MS, Parkinson’s and brain injury from all around our region. Through a method of support called Conductive Education, we teach life-changing skills such as sitting, standing, walking, speaking all in an environment where our children and adults can have fun, develop friendships and feel like they belong!

Pahar Trust Nepal helps to improve the standard of schools and education in the remote and impoverished areas of Nepal’s Himalayan foothills. For over 30 years, the Trust has delivered 250 individual projects and 656 classrooms, rebuilding many schools that were destroyed or damaged by the 2015 earthquake. The schools built by Pahar Trust Nepal are safe, secure and earthquake resistant, and equipped with updated resources and facilities, benefitting over 40,000 students in some of the world's poorest areas.

THE PAIN RELIEF FOUNDATION IS A UK CHARITY WHICH FUNDS RESEARCH INTO THE CAUSES AND TREATMENT OF HUMAN CHRONIC PAIN AND IS CONCERNED WITH EDUCATION OF HEALTH PROFESSIONALS ABOUT PAIN MANAGEMENT.

We focus on early diagnosis and awareness to improve survival of pancreatic cancer. Pancreatic Cancer Action and Pancreatic Cancer Scotland are now a merged organisation. United and stronger together we are determined to make the 2020’s a decade of change for pancreatic cancer. Thank you for your valued support, now and in the future. Early diagnosis of pancreatic cancer is key to survival. We are determined to make the 2020's the Decade of Change that pancreatic cancer needs.Our work has a direct impact on improving early diagnosis and supporting patients when they need us the most.

Pancreatic cancer has one of the lowest survival rates which has seen little improvement in 40 years. Pancreatic Cancer Research Fund is a small but dynamic charity, dedicated to defeating pancreatic cancer by funding innovative research into its detection and treatment.

Pancreatic Cancer UK is fighting to make a difference. We’re taking on pancreatic cancer together: by supporting those affected by the disease, investing in research, lobbying for greater recognition of pancreatic cancer, and being there for everyone involved in the fight. For too long this disease has been sidelined. We want to make sure that everyone touched by it gets the support and information they need. We’re here for everything you need to know about pancreatic cancer. We provide expert, personalised support and information via our Support Line and through a range of publications We fund innovative research to find the breakthroughs that will change how we understand, diagnose and treat pancreatic cancer We campaign for change; for better care, treatment and research, and for pancreatic cancer to have the recognition it needs.

PANDAS Foundation supports families affected by pre and post natal mental illnesses. Our Services are available throughout the UK in the form of local support groups, online peer support, email support and a helpline open 7 days a week 11am - 8pm. We rely on funding through donations and have a dedicated fundraising team available to answer any questions you may have about raising vital funds for PANDAS. To contact our fundraising team, please email: rachel.butler@pandasfoundation.org.uk Remember, it's OK not to be OK...

PANS PANDAS UK was established by a dedicated group of parents, whose children are living with PANS and PANDAS. Our vision is simple, to change how these conditions are diagnosed, treated, and understood by the medical community and the general public. So everyone living with PANS and PANDAS can look forward to a bright, healthy, and happy future.

PAPYRUS Prevention of Young Suicide is the UK charity dedicated to the prevention of suicide and the promotion of positive mental health and emotional wellbeing in young people. PAPYRUS exists to reduce the number of young people who take their own lives, by shattering the stigma surrounding suicide and equipping young people and their communities with the skills to recognise and respond to emotional distress.