We are a small children's charity which provides practical support to children with cancer or other life-limiting illnesses, and their families. We are also working to establish a purpose-built holiday home, which will be the first of its kind in this country, which will allow these families to spend precious time away together, free of charge.

Second Hope - is a UK charity dedicated to those living with or affected by advanced breast cancer (also called secondary, metastatic or Stage IV), when the cancer has spread and is incurable. Our mission - to provide hope and strength by raising awareness, providing support and funding research.

SeeAbility provides specialist support, accommodation and eye care help for people with learning disabilities, autism and sight loss.

SEED Madagascar is an award-winning, holistic international development charity who envisages communities and ecosystems thriving across Madagascar. Our central mission is to enhance the capacity of individuals, communities, organisations, and government in fulfilling sustainable environment, education, and development goals in southeast Madagascar. We achieve this by working across four departments to respond to the most critical and express needs of the country: community health, education infrastructure, sustainable livelihoods, and environmental conservation. Our approach is based on partnership, co-management, and skill-sharing with individuals, communities, local organisations, and governments. The programmes that result lead to lasting change, alleviating poverty and supporting environmental conservation for some of the world's most vulnerable people in threatened and irreplaceable environments, contributing to the UN's Sustainable Development Goals.

Send a Cow is a force for change in rural Africa. We help people grow their own futures – on their own land, on their own terms. Every day families face poverty that is extreme, cruel, and worst of all – unnecessary. But rural Africa is rich with opportunity and where there is land, there is hope. Send a Cow doesn’t impose solutions, we help grow them from within. That’s why they work. Our African-designed solutions were developed with, and for, the communities we support. Families get back the skills and confidence they need to get the most from their land. Families can grow enough food, earn a living and go after their dreams. And because the families we work with pass on what they know, success quickly multiplies, from family to family, community to community, generation to generation. Working across six African countries, we speak many languages. But in all of them, Send a Cow has come to mean a better future.

Sense is here to offer personalised support to help people communicate and experience the world. For everyone living with complex disabilities. For everyone who is deafblind. We believe that no one, no matter how complex their disabilities, should be isolated, left out, or unable to fulfil their potential. Our experts offer support that’s tailored to the individual needs of each person, whether that’s at our centres, through our holidays and short breaks, or in people’s own homes. In addition to practical support, we also provide information to families, and campaign for the rights of people with complex disabilities to take part in life.

We support individuals with sight loss, their families, carers and friends. We also provide advice to professionals, members of the public, community groups and anyone else who wants to make a positive difference to the lives of people with sight loss. We have a large network of local and national professionals who we can call on to support us such as GP’s, opticians and other charities.

Prince Harry set up Sentebale (which means, “forget me not”), to help the most vulnerable children in Southern Africa whose lives are shattered by HIV/Aids. Sentebale has changed the lives of thousands of children through care, health and education and giving them hope, and the opportunity to begin to enjoy their childhood.

Service by Emergency Rider Volunteers (SERV) provides a rapid and reliable means of transporting Emergency blood, blood products, X-rays, human infant milk, patient notes and laboratory samples to hospitals and medical facilities at night, free of charge.

Service Dogs UK serves the Armed Forces and Emergency Services communities. We pair veterans and serving personnel, who have been diagnosed with PTSD, with a carefully selected rescue dog and together they undertake our 9 - 12 month training programme to achieve ADI PTSD Assistance Dog Accreditation together. A lifelong partnership with a PTSD Assistance Dog greatly relieves the debilitating effects of PTSD, enabling the Veteran to re-engage with family and friends and start to enjoy life once more.

At Severn Hospice, our vision is a world where people are cared for at the end of their life as well as they were at its beginning. Our mission is to provide the best care and a better life for people living with an incurable illness, and for those important to them. Each year, over 2000 new patients from Shropshire, Mid Wales, Telford and Wrekin are embraced by our caring team. Can you help?

The UK's largest youth drama festival, offering students from all backgrounds the opportunity to perform Shakespeare on their local professional stage.

Set in an acre of woodland garden above the attractive coastal village of Shaldon, we look after, and help preserve, some of the rarest and most endangered animals in the world.

Shalva, the Israel Association for the Care and Inclusion of Persons with Disabilities is dedicated to providing transformative care for individuals with disabilities, empowering their families, and promoting social inclusion. Shalva provides an all-encompassing range of services for thousands of people with disabilities from infancy to adulthood and their families. Shalva’s comprehensive life-cycle programming provide leading-edge therapies, inclusive educational frameworks, social and recreational activities, employment training, and independent living, as well respite and family support. The Shalva National Center’s advanced programs and facilities create new frontiers in disability rehabilitation, research, and inclusion; defining new standards in the field and impacting the world beyond those in Shalva’s direct care. Shalva gives equal access and opportunity to all participants regardless of religion, ethnic background, or financial capability.

With your support, we help to improve the care of adults, children and babies being treated in all of the hospitals in Sheffield. Your donations fund specialist equipment, pioneering research, patient support services and the transformation of your hospitals into more comfortable, welcoming spaces.

We exist to defend the right to a safe home and fight the devastating impact the housing emergency has on people and society. We believe that home is everything.

HOME IS A HUMAN RIGHT. We exist to defend the right to a safe home in Wales and fight the devastating impact the housing emergency has on people and society. We do this with advice, support and campaigns – and we never give up. We believe that home is everything. Stand with us. Join the fight.

  ShelterBox is a disaster relief charity that provides shelter, warmth and dignity to those affected by disasters worldwide.  We deliver boxes of aid, each of which provides a family of ten with quality survival equipment to use while they rebuild their homes.    

Preschool that provides Early Education and childcare from aged 2.7 years until they go to school.

There are hundreds of orphans in Shewula with no one to pay for their education. The cost of fees, uniforms, stationery etc. means that most orphans/vulnerable children are simply unable to afford to go to school. With buildings part-funded by Truro College the Shewula programme has established three non-formal schools and one pre-school to serve the Shewula community. These Sebenta (non-formal) schools offer access to free education to orphans and vulnerable children.

Shine Bright Foundation was set in memory of our dear friend and family member Sarah Bennett. To raise awareness of Breast cancer, in particular Triple Negative Breast Cancer. We raise much needed funds for the research of TNBC and other breast cancers. We also provide holistic treatments for people having treatment for Breast Cancer locally to where we are based in Cheshire East. We also provide giftbags and comfort cushions nationally to those who request them, again to those who are having treatment for BC. More information is found on our web page www.shine-bright-foundation.org.uk

Shine Lincolnshire is a county wide charity which aims to support people with poor mental health to live well through accessing a range of support services, working with service users and carers and other agencies in Lincolnshire. We believe everyone deserves a life of value, enabling them to Shine.

Shooting Star Children’s Hospices cares for babies, children and young people with life-limiting conditions, and their families, across south-west London, north-west London and Surrey. We’re here to make every moment count, whether lives are measured in days, weeks, months, or years. We support families from diagnosis to end of life and throughout bereavement with a range of nursing, practical, emotional, and medical care. Our specialist care and support is free of charge and available 24 hours a day, 365 days a year. We support around 500 babies, children, or young adults who have a life-limiting condition and their families, as well as around 200 bereaved families. It costs £10 million a year to run Shooting Star Children’s Hospices, so we rely on the generosity of our supporters to keep our services going.

Powered by Mental Health Innovations, Shout is a free and confidential text messaging support service. It's available 24/7, for anyone in the UK who is struggling to cope and needs urgent support with their mental health.

Shropshire MHS supports everyone with their mental health, empowering you to live well with mental health.

Sight Support is a UK registered charity which provides support for people with sight loss in Hull and the East Riding. We believe no-one in Hull & East Yorkshire should have to face sight loss alone and every visually impaired person can enjoy the same opportunities and quality of life as those who are fully sighted. Our mission is to improve and enrich the quality of life for local people at all stages of sight loss, through the provision of a wide range of support services, enabling them to reach their full potential and lead independent lives. We currently support more than 2,300 local people with a range of visual impairments and work closely in partnership with local authorities, other local charities and a variety of support groups to provide the most appropriate support to suit each individual’s specific needs. We receive no government funding and rely on donations and gifts in wills to continue our work.

In the past 75 years, Sightsavers has achieved amazing things. We work in more than 30 countries to train health workers, provide eye operations, distribute treatment to prevent debilitating diseases, support people with disabilities, improve women’s health and more. In the seven decades since our foundation, we've distributed 1.7 billion treatments to prevent debilitating diseases, including blinding and potentially blinding conditions and carried out over 9.25 million cataract operations to save sight. Do a challenge event for Sightsavers and you can help make a huge difference. Just £33 could provide a sight restoring adult cataract operation to someone who thought they would never see again. We look forward to hearing from you and thank you for your support!

Last year over 500 young homeless people made their ‘home’ with us. YMCA Walthamstow is a supported housing scheme where accommodation and support are provided as a package. Our scheme is designed to help residents develop in all aspects of life; mind, body and spirit, enabling them to live with us then move onto independent living and sustainment within their community. We provide targeted and holistic support to single people aged 18 and above with housing and support needs, individuals who are homeless, vulnerable and/or at risk, people living with mental illness, learning disabilities or recovering from substance misuse or those who are fleeing domestic violence.